4uf0
From Proteopedia
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| - | + | ==Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.== | |
| - | + | <StructureSection load='4uf0' size='340' side='right' caption='[[4uf0]], [[Resolution|resolution]] 1.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4uf0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=MMK:2-{[(2-{[(E)-2-(DIMETHYLAMINO)ETHENYL](ETHYL)AMINO}-2-OXOETHYL)AMINO]METHYL}PYRIDINE-4-CARBOXYLIC+ACID'>MMK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uf0 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf0 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN]] Histone demethylase (By similarity). |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
| - | [[Category: | + | [[Category: Delft, F Von]] |
| + | [[Category: Edwards, A]] | ||
[[Category: Gileadi, C]] | [[Category: Gileadi, C]] | ||
| - | [[Category: Oppermann, U]] | ||
| - | [[Category: Kopec, J]] | ||
| - | [[Category: Von Delft, F]] | ||
[[Category: Johansson, C]] | [[Category: Johansson, C]] | ||
| - | [[Category: | + | [[Category: Kopec, J]] |
| + | [[Category: Oppermann, U]] | ||
[[Category: Srikannathasan, V]] | [[Category: Srikannathasan, V]] | ||
| + | [[Category: Tobias, K]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 13:46, 14 January 2015
Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.
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