2jfa
From Proteopedia
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- | [[Image:2jfa.gif|left|200px]] | + | [[Image:2jfa.gif|left|200px]] |
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- | '''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE''' | + | {{Structure |
+ | |PDB= 2jfa |SIZE=350|CAPTION= <scene name='initialview01'>2jfa</scene>, resolution 2.55Å | ||
+ | |SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+B'>AC1</scene> | ||
+ | |LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=RAL:RALOXIFENE'>RAL</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE''' | ||
+ | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
- | 2JFA is a [ | + | 2JFA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFA OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: zinc-finger]] | [[Category: zinc-finger]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:41:07 2008'' |
Revision as of 15:41, 20 March 2008
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, resolution 2.55Å | |||||||
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Ligands: | and | ||||||
Coordinates: | save as pdb, mmCIF, xml |
ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE
Disease
Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[133430], Breast cancer OMIM:[133430], Estrogen resistance OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]
About this Structure
2JFA is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 17:41:07 2008
Categories: Homo sapiens | Single protein | Gustafsson, J A. | Heldring, N. | Mcdonnell, D. | Pawson, T. | Pike, A C.W. | Treuter, E. | RAL | SO4 | Alternative splicing | Corepressor | Dna-binding | Ligand-binding domain (lbd) | Lipid-binding | Metal-binding | Nuclear protein | Nuclear receptor | Peptide antagonist | Phage display | Phosphorylation | Polymorphism | Receptor | Steroid-binding | Transcription | Transcription factor | Transcription regulation | Zinc | Zinc-finger