2exg
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2exg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EXG FirstGlance]. <br> | <table><tr><td colspan='2'>[[2exg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EXG FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STF:(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE'>STF</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STF:(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE'>STF</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2exg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2exg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2exg RCSB], [http://www.ebi.ac.uk/pdbsum/2exg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2exg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2exg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2exg RCSB], [http://www.ebi.ac.uk/pdbsum/2exg PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/AFAD_HUMAN AFAD_HUMAN]] Note=A chromosomal aberration involving MLLT4 is associated with acute leukemias. Translocation t(6;11)(q27;q23) with MLL/HRX. The result is a rogue activator protein. | [[http://www.uniprot.org/uniprot/AFAD_HUMAN AFAD_HUMAN]] Note=A chromosomal aberration involving MLLT4 is associated with acute leukemias. Translocation t(6;11)(q27;q23) with MLL/HRX. The result is a rogue activator protein. | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Boisguerin, P | + | [[Category: Boisguerin, P]] |
| - | [[Category: Joshi, M | + | [[Category: Joshi, M]] |
| - | [[Category: Krause, G | + | [[Category: Krause, G]] |
| - | [[Category: Oschkinat, H | + | [[Category: Oschkinat, H]] |
| - | [[Category: Schade, M | + | [[Category: Schade, M]] |
| - | [[Category: Vargas, C | + | [[Category: Vargas, C]] |
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Inhibitors of protein-protein interaction]] | [[Category: Inhibitors of protein-protein interaction]] | ||
Revision as of 18:07, 15 January 2015
Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain
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