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2iya

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iya]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_antibioticus Streptomyces antibioticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IYA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iya]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_antibioticus Streptomyces antibioticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IYA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene>, <scene name='pdbligand=ZIO:(3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL+2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE'>ZIO</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene>, <scene name='pdbligand=ZIO:(3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL+2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE'>ZIO</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iya OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iya RCSB], [http://www.ebi.ac.uk/pdbsum/2iya PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iya OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iya RCSB], [http://www.ebi.ac.uk/pdbsum/2iya PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Streptomyces antibioticus]]
[[Category: Streptomyces antibioticus]]
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[[Category: Bolam, D N.]]
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[[Category: Bolam, D N]]
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[[Category: Davies, G J.]]
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[[Category: Davies, G J]]
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[[Category: Davis, B G.]]
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[[Category: Davis, B G]]
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[[Category: Dodson, E J.]]
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[[Category: Dodson, E J]]
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[[Category: Gilbert, H J.]]
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[[Category: Gilbert, H J]]
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[[Category: Martinez-Fleites, C.]]
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[[Category: Martinez-Fleites, C]]
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[[Category: Proctor, M R.]]
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[[Category: Proctor, M R]]
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[[Category: Roberts, S M.]]
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[[Category: Roberts, S M]]
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[[Category: Turkenburg, J P.]]
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[[Category: Turkenburg, J P]]
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[[Category: Yang, M.]]
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[[Category: Yang, M]]
[[Category: Carbohydrate]]
[[Category: Carbohydrate]]
[[Category: Enzyme]]
[[Category: Enzyme]]

Revision as of 14:01, 19 January 2015

THE CRYSTAL STRUCTURE OF MACROLIDE GLYCOSYLTRANSFERASES: A BLUEPRINT FOR ANTIBIOTIC ENGINEERING

2iya, resolution 1.70Å

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