2nz2

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[[Image:2nz2.gif|left|200px]]<br /><applet load="2nz2" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2nz2.gif|left|200px]]
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caption="2nz2, resolution 2.40&Aring;" />
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'''Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline'''<br />
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{{Structure
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|PDB= 2nz2 |SIZE=350|CAPTION= <scene name='initialview01'>2nz2</scene>, resolution 2.40&Aring;
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|SITE= <scene name='pdbsite=AC1:ASP+Binding+Site+For+Residue+A+501'>AC1</scene> and <scene name='pdbsite=AC2:Cir+Binding+Site+For+Residue+A+502'>AC2</scene>
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|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene> and <scene name='pdbligand=CIR:CITRULLINE'>CIR</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Argininosuccinate_synthase Argininosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.5 6.3.4.5]
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|GENE= ASS1, ASS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2NZ2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=ASP:'>ASP</scene> and <scene name='pdbligand=CIR:'>CIR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Argininosuccinate_synthase Argininosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.5 6.3.4.5] Known structural/functional Sites: <scene name='pdbsite=AC1:ASP+Binding+Site+For+Residue+A+501'>AC1</scene> and <scene name='pdbsite=AC2:Cir+Binding+Site+For+Residue+A+502'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZ2 OCA].
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2NZ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZ2 OCA].
[[Category: Argininosuccinate synthase]]
[[Category: Argininosuccinate synthase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: ligase]]
[[Category: ligase]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: synthase]]
[[Category: synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 27 07:47:43 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:53:02 2008''

Revision as of 15:53, 20 March 2008

Image:2nz2.gif


PDB ID 2nz2

Drag the structure with the mouse to rotate
, resolution 2.40Å
Sites: and
Ligands: , and
Gene: ASS1, ASS (Homo sapiens)
Activity: Argininosuccinate synthase, with EC number 6.3.4.5
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline


Disease

Known disease associated with this structure: Citrullinemia OMIM:[603470]

About this Structure

2NZ2 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:53:02 2008

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OCA

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