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2vya

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vya]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VYA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vya]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VYA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VYA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PF7:4-(QUINOLIN-3-YLMETHYL)PIPERIDINE-1-CARBOXYLIC+ACID'>PF7</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PF7:4-(QUINOLIN-3-YLMETHYL)PIPERIDINE-1-CARBOXYLIC+ACID'>PF7</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mt5|1mt5]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mt5|1mt5]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Amidase Amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.4 3.5.1.4] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Amidase Amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.4 3.5.1.4] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vya OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vya RCSB], [http://www.ebi.ac.uk/pdbsum/2vya PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vya OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vya RCSB], [http://www.ebi.ac.uk/pdbsum/2vya PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Amidase]]
[[Category: Amidase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Ahn, K.]]
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[[Category: Ahn, K]]
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[[Category: Bhattacharya, K.]]
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[[Category: Bhattacharya, K]]
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[[Category: Cravatt, B F.]]
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[[Category: Cravatt, B F]]
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[[Category: Everdeen, D S.]]
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[[Category: Everdeen, D S]]
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[[Category: Johnson, D S.]]
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[[Category: Johnson, D S]]
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[[Category: Kamtekar, S.]]
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[[Category: Kamtekar, S]]
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[[Category: Liimatta, M.]]
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[[Category: Liimatta, M]]
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[[Category: Mileni, M.]]
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[[Category: Mileni, M]]
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[[Category: Nugent, R A.]]
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[[Category: Nugent, R A]]
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[[Category: Pabst, B.]]
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[[Category: Pabst, B]]
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[[Category: Stevens, R C.]]
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[[Category: Stevens, R C]]
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[[Category: Wang, Z.]]
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[[Category: Wang, Z]]
[[Category: Chimera]]
[[Category: Chimera]]
[[Category: Covalent]]
[[Category: Covalent]]

Revision as of 16:06, 19 January 2015

CRYSTAL STRUCTURE OF FATTY ACID AMIDE HYDROLASE CONJUGATED WITH THE DRUG-LIKE INHIBITOR PF-750

2vya, resolution 2.75Å

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