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2rug
From Proteopedia
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| - | ''' | + | ==Refined solution structure of the first RNA recognition motif domain in CPEB3== |
| + | <StructureSection load='2rug' size='340' side='right' caption='[[2rug]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2rug]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RUG FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rug OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rug RCSB], [http://www.ebi.ac.uk/pdbsum/2rug PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The family of cytoplasmic polyadenylation element binding proteins CPEB1, CPEB2, CPEB3, and CPEB4 binds to the 3'-untranslated region (3'-UTR) of mRNA, and plays significant roles in mRNA metabolism and translation regulation. They have a common domain organization, involving two consecutive RNA recognition motif (RRM) domains followed by a zinc finger domain in the C-terminal region. We solved the solution structure of the first RRM domain (RRM1) of human CPEB3, which revealed that CPEB3 RRM1 exhibits structural features distinct from those of the canonical RRM domain. Our structural data provide important information about the RNA binding ability of CPEB3 RRM1. | ||
| - | + | Novel RNA recognition motif domain in the cytoplasmic polyadenylation element binding protein 3.,Tsuda K, Kuwasako K, Nagata T, Takahashi M, Kigawa T, Kobayashi N, Guntert P, Shirouzu M, Yokoyama S, Muto Y Proteins. 2014 Oct;82(10):2879-86. doi: 10.1002/prot.24651. Epub 2014 Aug 11. PMID:25066254<ref>PMID:25066254</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Guntert, P]] | ||
| + | [[Category: Kigawa, T]] | ||
| + | [[Category: Kobayashi, N]] | ||
| + | [[Category: Kuwasako, K]] | ||
| + | [[Category: Muto, Y]] | ||
| + | [[Category: Nagata, T]] | ||
| + | [[Category: Shirouzu, M]] | ||
| + | [[Category: Takahashi, M]] | ||
| + | [[Category: Tsuda, K]] | ||
| + | [[Category: Yokoyama, S]] | ||
| + | [[Category: Rbd]] | ||
| + | [[Category: Rna binding protein]] | ||
| + | [[Category: Rrm domain]] | ||
Revision as of 16:22, 19 January 2015
Refined solution structure of the first RNA recognition motif domain in CPEB3
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Categories: Guntert, P | Kigawa, T | Kobayashi, N | Kuwasako, K | Muto, Y | Nagata, T | Shirouzu, M | Takahashi, M | Tsuda, K | Yokoyama, S | Rbd | Rna binding protein | Rrm domain
