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2vvt

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vvt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VVT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vvt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VVT FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=I24:2-BUTOXY-9-(2,6-DIFLUOROBENZYL)-N-(2-MORPHOLIN-4-YLETHYL)-9H-PURIN-6-AMINE'>I24</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=I24:2-BUTOXY-9-(2,6-DIFLUOROBENZYL)-N-(2-MORPHOLIN-4-YLETHYL)-9H-PURIN-6-AMINE'>I24</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jfp|2jfp]], [[2jfo|2jfo]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jfp|2jfp]], [[2jfo|2jfo]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_racemase Glutamate racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.3 5.1.1.3] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_racemase Glutamate racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.3 5.1.1.3] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vvt RCSB], [http://www.ebi.ac.uk/pdbsum/2vvt PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vvt RCSB], [http://www.ebi.ac.uk/pdbsum/2vvt PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Enterococcus faecalis]]
[[Category: Enterococcus faecalis]]
[[Category: Glutamate racemase]]
[[Category: Glutamate racemase]]
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[[Category: Breault, G.]]
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[[Category: Breault, G]]
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[[Category: Comita-Prevoir, J.]]
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[[Category: Comita-Prevoir, J]]
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[[Category: Doig, P.]]
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[[Category: Doig, P]]
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[[Category: Eyermann, C.]]
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[[Category: Eyermann, C]]
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[[Category: Geng, B.]]
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[[Category: Geng, B]]
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[[Category: Gorseth, E.]]
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[[Category: Gorseth, E]]
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[[Category: Lundqvist, T.]]
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[[Category: Lundqvist, T]]
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[[Category: Noonan, B.]]
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[[Category: Noonan, B]]
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[[Category: Petrichko, R.]]
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[[Category: Petrichko, R]]
[[Category: Benzyl purine]]
[[Category: Benzyl purine]]
[[Category: Cell shape]]
[[Category: Cell shape]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Cell wall biogenesis/degradation]]
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[[Category: Glutamate racemase]]
 
[[Category: Isomerase]]
[[Category: Isomerase]]
[[Category: Muri inhibitor]]
[[Category: Muri inhibitor]]
[[Category: Peptidoglycan synthesis]]
[[Category: Peptidoglycan synthesis]]

Revision as of 17:29, 19 January 2015

GLUTAMATE RACEMASE (MURI) FROM E. FAECALIS IN COMPLEX WITH A 9-BENZYL PURINE INHIBITOR

2vvt, resolution 1.65Å

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