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2vot
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOT FirstGlance]. <br> | <table><tr><td colspan='2'>[[2vot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOT FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NHV:(5R,6R,7S,8R)-6,7,8-TRIHYDROXY-5-(HYDROXYMETHYL)-2-[(PHENYLAMINO)METHYL]-5,6,7,8-TETRAHYDRO-1H-IMIDAZO[1,2-A]PYRIDIN-4-IUM'>NHV</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NHV:(5R,6R,7S,8R)-6,7,8-TRIHYDROXY-5-(HYDROXYMETHYL)-2-[(PHENYLAMINO)METHYL]-5,6,7,8-TETRAHYDRO-1H-IMIDAZO[1,2-A]PYRIDIN-4-IUM'>NHV</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vqt|2vqt]], [[2vl4|2vl4]], [[2vqu|2vqu]], [[2vo5|2vo5]], [[2je8|2je8]], [[2vjx|2vjx]], [[2vmf|2vmf]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vqt|2vqt]], [[2vl4|2vl4]], [[2vqu|2vqu]], [[2vo5|2vo5]], [[2je8|2je8]], [[2vjx|2vjx]], [[2vmf|2vmf]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-mannosidase Beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.25 3.2.1.25] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-mannosidase Beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.25 3.2.1.25] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vot RCSB], [http://www.ebi.ac.uk/pdbsum/2vot PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vot RCSB], [http://www.ebi.ac.uk/pdbsum/2vot PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Bacteroides thetaiotaomicron]] | [[Category: Bacteroides thetaiotaomicron]] | ||
[[Category: Beta-mannosidase]] | [[Category: Beta-mannosidase]] | ||
| - | [[Category: Bleriot, Y | + | [[Category: Bleriot, Y]] |
| - | [[Category: Davies, G J | + | [[Category: Davies, G J]] |
| - | [[Category: Dumon, C | + | [[Category: Dumon, C]] |
| - | [[Category: Gilbert, H J | + | [[Category: Gilbert, H J]] |
| - | [[Category: Gratien, J | + | [[Category: Gratien, J]] |
| - | [[Category: Heck, M P | + | [[Category: Heck, M P]] |
| - | [[Category: Moreland, C | + | [[Category: Moreland, C]] |
| - | [[Category: Offen, W A | + | [[Category: Offen, W A]] |
| - | [[Category: Smith, N | + | [[Category: Smith, N]] |
| - | [[Category: Stick, R V | + | [[Category: Stick, R V]] |
| - | [[Category: Tailford, L N | + | [[Category: Tailford, L N]] |
| - | [[Category: Vasella, A | + | [[Category: Vasella, A]] |
[[Category: Glycoside hydrolase]] | [[Category: Glycoside hydrolase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 18:15, 19 January 2015
STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
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Categories: Bacteroides thetaiotaomicron | Beta-mannosidase | Bleriot, Y | Davies, G J | Dumon, C | Gilbert, H J | Gratien, J | Heck, M P | Moreland, C | Offen, W A | Smith, N | Stick, R V | Tailford, L N | Vasella, A | Glycoside hydrolase | Hydrolase | Linear free energy relationship | Mannosidase | Transition state mimic
