2obv

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[[Image:2obv.gif|left|200px]]<br /><applet load="2obv" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2obv.gif|left|200px]]
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caption="2obv, resolution 2.05&Aring;" />
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'''Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product'''<br />
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{{Structure
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|PDB= 2obv |SIZE=350|CAPTION= <scene name='initialview01'>2obv</scene>, resolution 2.05&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene> and <scene name='pdbligand=PG4:TETRAETHYLENE GLYCOL'>PG4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6]
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|GENE= MAT1A, AMS1, MATA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2OBV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=SAM:'>SAM</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBV OCA].
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2OBV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBV OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Methionine adenosyltransferase]]
[[Category: Methionine adenosyltransferase]]
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[[Category: SAM]]
[[Category: SAM]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: synthetase]]
[[Category: synthetase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:16:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:57:38 2008''

Revision as of 15:57, 20 March 2008

Image:2obv.gif


PDB ID 2obv

Drag the structure with the mouse to rotate
, resolution 2.05Å
Ligands: , and
Gene: MAT1A, AMS1, MATA1 (Homo sapiens)
Activity: Methionine adenosyltransferase, with EC number 2.5.1.6
Coordinates: save as pdb, mmCIF, xml



Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product


Disease

Known diseases associated with this structure: Hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase I/III deficiency OMIM:[250850], Methionine adenosyltransferase deficiency, autosomal recessive OMIM:[250850]

About this Structure

2OBV is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:57:38 2008

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