2ocf

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[[Image:2ocf.jpg|left|200px]]<br /><applet load="2ocf" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2ocf.jpg|left|200px]]
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caption="2ocf, resolution 2.95&Aring;" />
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'''Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody'''<br />
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{{Structure
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|PDB= 2ocf |SIZE=350|CAPTION= <scene name='initialview01'>2ocf</scene>, resolution 2.95&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=EST:ESTRADIOL'>EST</scene>
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|ACTIVITY=
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|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CIG, FN1, FN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2OCF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=EST:'>EST</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OCF OCA].
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2OCF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OCF OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: monobody]]
[[Category: monobody]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:16:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:57:53 2008''

Revision as of 15:57, 20 March 2008


PDB ID 2ocf

Drag the structure with the mouse to rotate
, resolution 2.95Å
Ligands:
Gene: ESR1, ESR, NR3A1 (Homo sapiens), CIG, FN1, FN (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody


Disease

Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[133430], Breast cancer OMIM:[133430], Ehlers-Danlos syndrome, type X, 225310 (1) OMIM:[135600], Estrogen resistance OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]

About this Structure

2OCF is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:57:53 2008

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