3a2o
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3a2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2O FirstGlance]. <br> | <table><tr><td colspan='2'>[[3a2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2O FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KNJ:(4R)-3-[(2S,3S)-3-{[(4-AMINO-2,6-DIMETHYLPHENOXY)ACETYL]AMINO}-2-HYDROXY-4-PHENYLBUTANOYL]-5,5-DIMETHYL-N-(2-METHYLPROP-2-EN-1-YL)-1,3-THIAZOLIDINE-4-CARBOXAMIDE'>KNJ</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KNJ:(4R)-3-[(2S,3S)-3-{[(4-AMINO-2,6-DIMETHYLPHENOXY)ACETYL]AMINO}-2-HYDROXY-4-PHENYLBUTANOYL]-5,5-DIMETHYL-N-(2-METHYLPROP-2-EN-1-YL)-1,3-THIAZOLIDINE-4-CARBOXAMIDE'>KNJ</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hpx|1hpx]], [[2zye|2zye]], [[3fx5|3fx5]], [[1msm|1msm]], [[1msn|1msn]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hpx|1hpx]], [[2zye|2zye]], [[3fx5|3fx5]], [[1msm|1msm]], [[1msn|1msn]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a2o RCSB], [http://www.ebi.ac.uk/pdbsum/3a2o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a2o RCSB], [http://www.ebi.ac.uk/pdbsum/3a2o PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| - | [[Category: Adachi, M | + | [[Category: Adachi, M]] |
| - | [[Category: Hidaka, K | + | [[Category: Hidaka, K]] |
| - | [[Category: Kimura, T | + | [[Category: Kimura, T]] |
| - | [[Category: Kiso, Y | + | [[Category: Kiso, Y]] |
| - | [[Category: Kuroki, R | + | [[Category: Kuroki, R]] |
| - | [[Category: Tamada, T | + | [[Category: Tamada, T]] |
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Hiv-1 protease]] | [[Category: Hiv-1 protease]] | ||
Revision as of 09:28, 20 January 2015
Crystal Structure of HIV-1 Protease Complexed with KNI-1689
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