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3dyg

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3dyg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DYG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3dyg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DYG FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NI9:3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM'>NI9</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NI9:3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM'>NI9</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ewg|2ewg]], [[2i19|2i19]], [[2ogd|2ogd]], [[3dyf|3dyf]], [[3dyh|3dyh]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ewg|2ewg]], [[2i19|2i19]], [[2ogd|2ogd]], [[3dyf|3dyf]], [[3dyh|3dyh]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Geranyltranstransferase Geranyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Geranyltranstransferase Geranyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dyg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dyg RCSB], [http://www.ebi.ac.uk/pdbsum/3dyg PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dyg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dyg RCSB], [http://www.ebi.ac.uk/pdbsum/3dyg PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Geranyltranstransferase]]
[[Category: Geranyltranstransferase]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Cao, R.]]
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[[Category: Cao, R]]
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[[Category: Gao, Y.]]
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[[Category: Gao, Y]]
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[[Category: Goddard, A.]]
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[[Category: Goddard, A]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield, E]]
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[[Category: Robinson, H.]]
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[[Category: Robinson, H]]
[[Category: Isoprene biosynthesis]]
[[Category: Isoprene biosynthesis]]
[[Category: Protein-bisphosphonate complex]]
[[Category: Protein-bisphosphonate complex]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 10:54, 20 January 2015

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461

3dyg, resolution 2.10Å

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