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2woa

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2woa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2woa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=576:(3S)-5-(9H-FLUOREN-2-YL)-3-HYDROXYPENTANOIC+ACID'>576</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=576:(3S)-5-(9H-FLUOREN-2-YL)-3-HYDROXYPENTANOIC+ACID'>576</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[1os9|1os9]], [[1utt|1utt]], [[1z3j|1z3j]], [[1y93|1y93]], [[2wo8|2wo8]], [[2w0d|2w0d]], [[1os2|1os2]], [[2wo9|2wo9]], [[1ros|1ros]], [[1jk3|1jk3]], [[1utz|1utz]], [[1jiz|1jiz]], [[1rmz|1rmz]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[1os9|1os9]], [[1utt|1utt]], [[1z3j|1z3j]], [[1y93|1y93]], [[2wo8|2wo8]], [[2w0d|2w0d]], [[1os2|1os2]], [[2wo9|2wo9]], [[1ros|1ros]], [[1jk3|1jk3]], [[1utz|1utz]], [[1jiz|1jiz]], [[1rmz|1rmz]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2woa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2woa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2woa RCSB], [http://www.ebi.ac.uk/pdbsum/2woa PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2woa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2woa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2woa RCSB], [http://www.ebi.ac.uk/pdbsum/2woa PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Macrophage elastase]]
[[Category: Macrophage elastase]]
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[[Category: Amour, A J.]]
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[[Category: Amour, A J]]
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[[Category: Baddeley, S J.]]
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[[Category: Baddeley, S J]]
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[[Category: Brown, D.]]
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[[Category: Brown, D]]
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[[Category: Convery, M A.]]
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[[Category: Convery, M A]]
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[[Category: Egan, D.]]
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[[Category: Egan, D]]
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[[Category: Gaines, S.]]
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[[Category: Gaines, S]]
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[[Category: Gross, J W.]]
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[[Category: Gross, J W]]
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[[Category: Herbert, S.]]
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[[Category: Herbert, S]]
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[[Category: Holmes, I P.]]
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[[Category: Holmes, I P]]
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[[Category: Lorthioir, O.]]
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[[Category: Lorthioir, O]]
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[[Category: Martin, S L.]]
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[[Category: Martin, S L]]
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[[Category: Singh, O M.P.]]
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[[Category: Singh, O M.P]]
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[[Category: Smith, R H.]]
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[[Category: Smith, R H]]
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[[Category: Strelow, J M.]]
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[[Category: Strelow, J M]]
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[[Category: Walker, A.]]
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[[Category: Walker, A]]
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[[Category: Watson, S P.]]
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[[Category: Watson, S P]]
[[Category: Disulfide bond]]
[[Category: Disulfide bond]]
[[Category: Extracellular matrix]]
[[Category: Extracellular matrix]]

Revision as of 11:42, 20 January 2015

MMP12 COMPLEX WITH A BETA HYDROXY CARBOXYLIC ACID

2woa, resolution 2.30Å

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