Acetyl-CoA synthetase
From Proteopedia
(Difference between revisions)
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| - | [[1pg3]], [[1pg4]] – | + | [[1pg3]], [[1pg4]] – SeACS (mutant) + CoA + AMP – ''Salmonella enterica''<br /> |
[[2p20]], [[2p2m]], [[2p2q]] - StACS (mutant) + AMP – ''Salmonella typhimurium''<br /> | [[2p20]], [[2p2m]], [[2p2q]] - StACS (mutant) + AMP – ''Salmonella typhimurium''<br /> | ||
[[2p2b]], [[2p2j]] - StACS (mutant) + CoA + AMP<br /> | [[2p2b]], [[2p2j]] - StACS (mutant) + CoA + AMP<br /> | ||
[[2p2f]] - StACS + CoA + AMP<br /> | [[2p2f]] - StACS + CoA + AMP<br /> | ||
| - | [[1ry2]] – ACS + AMP - yeast | + | [[1ry2]] – ACS + AMP - yeast<br /> |
| + | [[4u5y]] – ACS GNAT domain + SeACS C terminal (mutant) – ''Streptomyces lividans''<br /> | ||
Revision as of 11:50, 21 January 2015
Acetyl-CoA synthetase (ACS) catalyzes the ligation of acetate and CoA to form acetyl-CoA with the conversion of ATP to AMP and pyrophosphate. The acetyl-CoA is used in aerobic respiration to produce energy and electron carriers and for lipid biosynthesis. ACS is an ATP-dependent AMP-binding enzyme.
3D structures of acetyl-CoA synthetase
Updated on 21-January-2015
1pg3, 1pg4 – SeACS (mutant) + CoA + AMP – Salmonella enterica
2p20, 2p2m, 2p2q - StACS (mutant) + AMP – Salmonella typhimurium
2p2b, 2p2j - StACS (mutant) + CoA + AMP
2p2f - StACS + CoA + AMP
1ry2 – ACS + AMP - yeast
4u5y – ACS GNAT domain + SeACS C terminal (mutant) – Streptomyces lividans
