4u7d

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'''Unreleased structure'''
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==Structure of human RECQ-like helicase in complex with an oligonucleotide==
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<StructureSection load='4u7d' size='340' side='right' caption='[[4u7d]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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The entry 4u7d is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4u7d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U7D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U7D FirstGlance]. <br>
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Authors: Pike, A.C.W., Zhang, Y., Schnecke, C., Cooper, C.D.O., Von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O., Structural Genomics Consortium (SGC)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
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Description: Structure of human RECQ-like helicase in complex with an oligonucleotide
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u7d RCSB], [http://www.ebi.ac.uk/pdbsum/4u7d PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Pike, A.C.W]]
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== Function ==
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[[Category: Zhang, Y]]
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[[http://www.uniprot.org/uniprot/RECQ1_HUMAN RECQ1_HUMAN]] DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.<ref>PMID:15886194</ref> <ref>PMID:7961977</ref> <ref>PMID:8056767</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: DNA helicase]]
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[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]
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[[Category: Schnecke, C]]
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[[Category: Cooper, C D.O]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Delft, F Von]]
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[[Category: Von Delft, F]]
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[[Category: Gileadi, O]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Edwards, A]]
[[Category: Edwards, A]]
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[[Category: Cooper, C.D.O]]
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[[Category: Gileadi, O]]
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[[Category: Pike, A C.W]]
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[[Category: Structural genomic]]
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[[Category: Schnecke, C]]
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[[Category: Zhang, Y]]
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[[Category: Dna binding protein]]
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[[Category: Dna strand annealing]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Nuclear protein]]
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[[Category: Sgc]]

Revision as of 17:00, 21 January 2015

Structure of human RECQ-like helicase in complex with an oligonucleotide

4u7d, resolution 3.40Å

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