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4x33
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Structure of the Elongator cofactor complex Kti11/Kti13 at 1.45A== |
| - | + | <StructureSection load='4x33' size='340' side='right' caption='[[4x33]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x33]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X33 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X33 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DXE:1,2-DIMETHOXYETHANE'>DXE</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x33 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x33 RCSB], [http://www.ebi.ac.uk/pdbsum/4x33 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPH3_YEAST DPH3_YEAST]] Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. Required for conferring sensitivity to K.lactis zymocin.<ref>PMID:15485916</ref> [[http://www.uniprot.org/uniprot/ATS1_YEAST ATS1_YEAST]] May participate in regulatory interactions between microtubules and the cell cycle. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Cavarelli, J]] | [[Category: Cavarelli, J]] | ||
| - | [[Category: Mcewen, A.G]] | ||
[[Category: Kolaj-Robin, O]] | [[Category: Kolaj-Robin, O]] | ||
| + | [[Category: McEwen, A G]] | ||
[[Category: Seraphin, B]] | [[Category: Seraphin, B]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Electron transfer]] | ||
| + | [[Category: Electron transport]] | ||
| + | [[Category: Trna modification]] | ||
Revision as of 17:01, 21 January 2015
Structure of the Elongator cofactor complex Kti11/Kti13 at 1.45A
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