2yps
From Proteopedia
(Difference between revisions)
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<StructureSection load='2yps' size='340' side='right' caption='[[2yps]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2yps' size='340' side='right' caption='[[2yps]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yps]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YPS FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2yps]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YPS FirstGlance]. <br> |
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yps OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yps RCSB], [http://www.ebi.ac.uk/pdbsum/2yps PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yps OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yps RCSB], [http://www.ebi.ac.uk/pdbsum/2yps PDBsum]</span></td></tr> | ||
</table> | </table> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/SNX3_HUMAN SNX3_HUMAN]] Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Plays a role in protein transport between cellular compartments. Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G (By similarity). Not involved in EGFR degradation.<ref>PMID:11433298</ref> <ref>PMID:18767904</ref> | [[http://www.uniprot.org/uniprot/SNX3_HUMAN SNX3_HUMAN]] Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Plays a role in protein transport between cellular compartments. Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G (By similarity). Not involved in EGFR degradation.<ref>PMID:11433298</ref> <ref>PMID:18767904</ref> | ||
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| + | ==See Also== | ||
| + | *[[Sorting nexin|Sorting nexin]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Human]] |
| - | [[Category: Bountra, C | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Canning, P | + | [[Category: Bountra, C]] |
| - | [[Category: Delft, F von | + | [[Category: Canning, P]] |
| - | [[Category: Edwards, A M | + | [[Category: Delft, F von]] |
| - | [[Category: Froese, D S | + | [[Category: Edwards, A M]] |
| - | [[Category: Kiyani, W | + | [[Category: Froese, D S]] |
| - | [[Category: Krojer, T | + | [[Category: Kiyani, W]] |
| - | [[Category: Strain-Damerell, C | + | [[Category: Krojer, T]] |
| - | [[Category: Yue, W W | + | [[Category: Strain-Damerell, C]] |
| + | [[Category: Yue, W W]] | ||
[[Category: Endosome]] | [[Category: Endosome]] | ||
[[Category: Protein transport]] | [[Category: Protein transport]] | ||
Revision as of 09:32, 25 January 2015
Crystal structure of the PX domain of human sorting nexin 3
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