2p6x

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[[Image:2p6x.jpg|left|200px]]<br /><applet load="2p6x" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2p6x.jpg|left|200px]]
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caption="2p6x, resolution 1.90&Aring;" />
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'''Crystal structure of human tyrosine phosphatase PTPN22'''<br />
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{{Structure
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|PDB= 2p6x |SIZE=350|CAPTION= <scene name='initialview01'>2p6x</scene>, resolution 1.90&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
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|GENE= PTPN22, PTPN8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of human tyrosine phosphatase PTPN22'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2P6X is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P6X OCA].
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2P6X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P6X OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: pep]]
[[Category: pep]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: tyrosine phosphatase]]
[[Category: tyrosine phosphatase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:26:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:09:35 2008''

Revision as of 16:09, 20 March 2008

Image:2p6x.jpg


PDB ID 2p6x

Drag the structure with the mouse to rotate
, resolution 1.90Å
Ligands: and
Gene: PTPN22, PTPN8 (Homo sapiens)
Activity: Protein-tyrosine-phosphatase, with EC number 3.1.3.48
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human tyrosine phosphatase PTPN22


Disease

Known diseases associated with this structure: Diabetes mellitus, insulin-dependent, susceptibility to OMIM:[600716], Rheumatoid arthritis, susceptibility to OMIM:[600716], Systemic lupus erythematosus, susceptibility to OMIM:[600716]

About this Structure

2P6X is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:09:35 2008

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