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2p8u
From Proteopedia
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| - | [[Image:2p8u.gif|left|200px]] | + | [[Image:2p8u.gif|left|200px]] |
| - | + | ||
| - | '''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I''' | + | {{Structure |
| + | |PDB= 2p8u |SIZE=350|CAPTION= <scene name='initialview01'>2p8u</scene>, resolution 2.00Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10] | ||
| + | |GENE= HMGCS1, HMGCS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I''' | ||
| + | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2P8U is a [ | + | 2P8U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8U OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hydroxymethylglutaryl-CoA synthase]] | [[Category: Hydroxymethylglutaryl-CoA synthase]] | ||
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[[Category: mevalonate pathway]] | [[Category: mevalonate pathway]] | ||
[[Category: sgc]] | [[Category: sgc]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:10:13 2008'' |
Revision as of 16:10, 20 March 2008
| |||||||
| , resolution 2.00Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | and | ||||||
| Gene: | HMGCS1, HMGCS (Homo sapiens) | ||||||
| Activity: | Hydroxymethylglutaryl-CoA synthase, with EC number 2.3.3.10 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I
Disease
Known disease associated with this structure: HMG-CoA synthase-2 deficiency OMIM:[600234]
About this Structure
2P8U is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:10:13 2008
Categories: Homo sapiens | Hydroxymethylglutaryl-CoA synthase | Single protein | Arrowsmith, C H. | Bunkoczi, G. | Burgess, N. | Debreczeni, J. | Delft, F von. | Edwards, A. | Gorrec, F. | Niesen, F H. | Oppermann, U. | Pike, A C.W. | SGC, Structural Genomics Consortium. | Salah, E. | Shafqat, N. | Sundstrom, M. | Turnbull, A P. | Umeano, C. | Weigelt, J. | COA | GOL | Hydromethylglutaryl coa | Mevalonate pathway | Sgc | Structural genomic | Structural genomics consortium
