2p8u

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[[Image:2p8u.gif|left|200px]]<br /><applet load="2p8u" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2p8u.gif|left|200px]]
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caption="2p8u, resolution 2.00&Aring;" />
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'''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I'''<br />
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{{Structure
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|PDB= 2p8u |SIZE=350|CAPTION= <scene name='initialview01'>2p8u</scene>, resolution 2.00&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10]
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|GENE= HMGCS1, HMGCS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2P8U is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=COA:'>COA</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_synthase Hydroxymethylglutaryl-CoA synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.10 2.3.3.10] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8U OCA].
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2P8U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8U OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hydroxymethylglutaryl-CoA synthase]]
[[Category: Hydroxymethylglutaryl-CoA synthase]]
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[[Category: mevalonate pathway]]
[[Category: mevalonate pathway]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:27:07 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:10:13 2008''

Revision as of 16:10, 20 March 2008

Image:2p8u.gif


PDB ID 2p8u

Drag the structure with the mouse to rotate
, resolution 2.00Å
Ligands: and
Gene: HMGCS1, HMGCS (Homo sapiens)
Activity: Hydroxymethylglutaryl-CoA synthase, with EC number 2.3.3.10
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I


Disease

Known disease associated with this structure: HMG-CoA synthase-2 deficiency OMIM:[600234]

About this Structure

2P8U is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:10:13 2008

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