4v0r

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'''Unreleased structure'''
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==DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH==
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<StructureSection load='4v0r' size='340' side='right' caption='[[4v0r]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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The entry 4v0r is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4v0r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V0R FirstGlance]. <br>
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Authors: ZHAO, Y., SOH, S., ZHENG, J., PHOO, W.W., SWAMINATHAN, K., CORNVIK, T.C., LIM, S.P., SHI, P.-Y., LESCAR, J., VASUDEVAN, S.G., LUO, D.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4v0q|4v0q]]</td></tr>
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Description: DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v0r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v0r RCSB], [http://www.ebi.ac.uk/pdbsum/4v0r PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Lim, S.P]]
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== Function ==
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[[Category: Soh, S]]
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[[http://www.uniprot.org/uniprot/Q6DLV0_9FLAV Q6DLV0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
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__TOC__
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</StructureSection>
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[[Category: Cornvik, T C]]
[[Category: Lescar, J]]
[[Category: Lescar, J]]
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[[Category: Lim, S P]]
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[[Category: Luo, D]]
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[[Category: Phoo, W W]]
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[[Category: Shi, P Y]]
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[[Category: Soh, S]]
[[Category: Swaminathan, K]]
[[Category: Swaminathan, K]]
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[[Category: Shi, P.-Y]]
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[[Category: Vasudevan, S G]]
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[[Category: Cornvik, T.C]]
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[[Category: Zhao, Y]]
[[Category: Zhao, Y]]
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[[Category: Phoo, W.W]]
 
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[[Category: Vasudevan, S.G]]
 
[[Category: Zheng, J]]
[[Category: Zheng, J]]
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[[Category: Luo, D]]
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[[Category: Methyltransferase]]
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[[Category: Rna-dependent rna polymerase]]
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[[Category: Transferase]]

Revision as of 16:49, 28 January 2015

DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH

4v0r, resolution 2.40Å

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