This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3wsz
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==SorLA Vps10p domain in complex with Abeta-derived peptide== |
| - | + | <StructureSection load='3wsz' size='340' side='right' caption='[[3wsz]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3wsz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WSZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wsx|3wsx]], [[3wsy|3wsy]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wsz RCSB], [http://www.ebi.ac.uk/pdbsum/3wsz PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SORL_HUMAN SORL_HUMAN]] Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kitago, Y]] | ||
| + | [[Category: Nagae, M]] | ||
| + | [[Category: Nakata, Z]] | ||
[[Category: Nogi, T]] | [[Category: Nogi, T]] | ||
[[Category: Takagi, J]] | [[Category: Takagi, J]] | ||
| - | [[Category: | + | [[Category: Beta-propeller]] |
| - | [[Category: | + | [[Category: Protein binding]] |
| - | [[Category: | + | [[Category: Receptor]] |
Revision as of 15:53, 7 February 2015
SorLA Vps10p domain in complex with Abeta-derived peptide
| |||||||||||
Categories: Kitago, Y | Nagae, M | Nakata, Z | Nogi, T | Takagi, J | Beta-propeller | Protein binding | Receptor
