4s0w

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m (Protected "4s0w" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Wild type T4 lysozyme structure==
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<StructureSection load='4s0w' size='340' side='right' caption='[[4s0w]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
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The entry 4s0w is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4s0w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S0W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S0W FirstGlance]. <br>
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Authors: Snell, E.H., Snell, M.E.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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Description: Wild type T4 lysozyme structure
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s0w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4s0w RCSB], [http://www.ebi.ac.uk/pdbsum/4s0w PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Snell, E.H]]
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== Function ==
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[[Category: Snell, M.E]]
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[[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Lysozyme]]
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[[Category: Snell, E H]]
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[[Category: Snell, M E]]
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[[Category: Hydrolase]]

Revision as of 15:59, 7 February 2015

Wild type T4 lysozyme structure

4s0w, resolution 2.12Å

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