4unk
From Proteopedia
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| - | ''' | + | ==Crystal structure of human triosephosphate isomerase (mutant N15D)== |
| - | + | <StructureSection load='4unk' size='340' side='right' caption='[[4unk]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4unk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UNK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UNK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4unl|4unl]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4unk RCSB], [http://www.ebi.ac.uk/pdbsum/4unk PDBsum]</span></td></tr> | |
| - | [ | + | </table> |
| - | [ | + | == Disease == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[http://omim.org/entry/190450 190450]]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Triose-phosphate isomerase]] | ||
[[Category: Castillo-Villanueva, A]] | [[Category: Castillo-Villanueva, A]] | ||
| - | [[Category: | + | [[Category: DeLaMora-DeLaMora, I]] |
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[[Category: Enriquez-Flores, S]] | [[Category: Enriquez-Flores, S]] | ||
| - | [[Category: Torres- | + | [[Category: Garcia-Torres, I]] |
| + | [[Category: Gomez-Manzo, S]] | ||
| + | [[Category: Lopez-Velazquez, G]] | ||
[[Category: Marcial-Quino, J]] | [[Category: Marcial-Quino, J]] | ||
| + | [[Category: Mendez, S T]] | ||
| + | [[Category: Oria-Hernandez, J]] | ||
| + | [[Category: Reyes-Vivas, H]] | ||
[[Category: Torres-Arroyo, A]] | [[Category: Torres-Arroyo, A]] | ||
| + | [[Category: Torres-Larios, A]] | ||
| + | [[Category: Deamidation]] | ||
| + | [[Category: Isomerase]] | ||
Revision as of 15:59, 7 February 2015
Crystal structure of human triosephosphate isomerase (mutant N15D)
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