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4wvo

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'''Unreleased structure'''
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==An engineered PYR1 mandipropamid receptor in complex with mandipropamid and HAB1==
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<StructureSection load='4wvo' size='340' side='right' caption='[[4wvo]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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The entry 4wvo is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4wvo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WVO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WVO FirstGlance]. <br>
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Authors: Peterson, F.C., Volkman, B.F., Cutler, S.R.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3UZ:(2S)-2-(4-CHLOROPHENYL)-N-{2-[3-METHOXY-4-(PROP-2-YN-1-YLOXY)PHENYL]ETHYL}-2-(PROP-2-YN-1-YLOXY)ETHANAMIDE'>3UZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr>
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Description: An engineered PYR1 mandipropamid receptor in complex with mandipropamid and HAB1
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wvo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wvo RCSB], [http://www.ebi.ac.uk/pdbsum/4wvo PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Cutler, S.R]]
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== Function ==
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[[Category: Peterson, F.C]]
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[[http://www.uniprot.org/uniprot/PYR1_ARATH PYR1_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19624469</ref> <ref>PMID:19407142</ref> <ref>PMID:19769575</ref> [[http://www.uniprot.org/uniprot/P2C16_ARATH P2C16_ARATH]] Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. Confers enhanced sensitivity to drought.<ref>PMID:14731256</ref> <ref>PMID:16876791</ref> <ref>PMID:16798945</ref> <ref>PMID:19033529</ref>
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[[Category: Volkman, B.F]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Phosphoprotein phosphatase]]
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[[Category: Cutler, S R]]
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[[Category: Peterson, F C]]
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[[Category: Volkman, B F]]
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[[Category: Hab1]]
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[[Category: Hydrolase-hydrolase inthibitor complex]]
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[[Category: Mandipropamid]]
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[[Category: Pp2c inhibitor]]
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[[Category: Pyr/pyl/rcar]]
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[[Category: Pyr1]]

Revision as of 12:05, 12 February 2015

An engineered PYR1 mandipropamid receptor in complex with mandipropamid and HAB1

4wvo, resolution 2.25Å

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