4x4r
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACC and AMPcPP== |
| - | + | <StructureSection load='4x4r' size='340' side='right' caption='[[4x4r]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x4r]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X4R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X4R FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x4n|4x4n]], [[4x4o|4x4o]], [[4x4p|4x4p]], [[4x4q|4x4q]], [[4x4s|4x4s]], [[4x4t|4x4t]], [[4x4u|4x4u]], [[4x4v|4x4v]], [[4x4w|4x4w]], [[4x4x|4x4x]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CCA_tRNA_nucleotidyltransferase CCA tRNA nucleotidyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.72 2.7.7.72] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x4r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x4r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x4r RCSB], [http://www.ebi.ac.uk/pdbsum/4x4r PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CCA_ARCFU CCA_ARCFU]] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<ref>PMID:14592988</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: CCA tRNA nucleotidyltransferase]] | ||
[[Category: Joshua-Tor, L]] | [[Category: Joshua-Tor, L]] | ||
| - | [[Category: Kuhn, C | + | [[Category: Kuhn, C D]] |
| + | [[Category: Cca-adding enzyme]] | ||
| + | [[Category: Ncrna]] | ||
| + | [[Category: Non-coding rna]] | ||
| + | [[Category: Nucleotidyltransferase]] | ||
| + | [[Category: Protein-rna complex]] | ||
| + | [[Category: Rna binding protein]] | ||
| + | [[Category: Trna]] | ||
Revision as of 12:05, 12 February 2015
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACC and AMPcPP
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