4xwa

From Proteopedia

proteopedia linkproteopedia link

Revision as of 14:54, 7 February 2015 (edit) OCA (Talk | contribs) m (Protected "4xwa" [edit=sysop:move=sysop]) ← Previous diff		Revision as of 12:07, 12 February 2015 (edit) (undo) OCA (Talk | contribs) Next diff →
Line 1:		Line 1:
-	'''Unreleased structure'''	+	==TMK from S.aureus in complex with the Piperidinyl Thymine class inhibitor with a C5 ethyl-amine==
-		+	<StructureSection load='4xwa' size='340' side='right' caption='[[4xwa]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
-	The entry 4xwa is ON HOLD	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4xwa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XWA FirstGlance]. <br>
-	Authors: Olivier, N.B.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=43N:2-(3-CHLOROPHENOXY)-6-(ETHYLAMINO)-4-[(R)-[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)PIPERIDIN-1-YL](PHENYL)METHYL]BENZOIC+ACID'>43N</scene></td></tr>
-		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
-	Description: TMK from S.aureus in complex with the Piperidinyl Thymine class inhibitor with a C5 ethyl-amine	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xwa RCSB], [http://www.ebi.ac.uk/pdbsum/4xwa PDBsum]</span></td></tr>
-	[[Category: Unreleased Structures]]	+	</table>
-	[[Category: Olivier, N.B]]	+	== Function ==
		+	[[http://www.uniprot.org/uniprot/KTHY_STAA1 KTHY_STAA1]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: DTMP kinase]]
		+	[[Category: Olivier, N B]]
		+	[[Category: Antibacterial]]
		+	[[Category: Kinase]]
		+	[[Category: Piperidine]]
		+	[[Category: Thymidine]]
		+	[[Category: Tmk]]
		+	[[Category: Transferase]]

---

Revision as of 12:07, 12 February 2015

TMK from S.aureus in complex with the Piperidinyl Thymine class inhibitor with a C5 ethyl-amine

spinqualitylabelsall models 4xwa, resolution 1.89Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structural highlights 4xwa is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Activity: dTMP kinase, with EC number 2.7.4.9 Resources: FirstGlance, OCA, RCSB, PDBsum Function [KTHY_STAA1] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. Contents 1 Structural highlights 2 Function