2pw8
From Proteopedia
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- | [[Image:2pw8.jpg|left|200px]] | + | [[Image:2pw8.jpg|left|200px]] |
- | + | ||
- | '''Crystal structure of sulfo-hirudin complexed to thrombin''' | + | {{Structure |
+ | |PDB= 2pw8 |SIZE=350|CAPTION= <scene name='initialview01'>2pw8</scene>, resolution 1.840Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene> and <scene name='pdbligand=NA:SODIUM ION'>NA</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''Crystal structure of sulfo-hirudin complexed to thrombin''' | ||
+ | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
- | 2PW8 is a [ | + | 2PW8 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PW8 OCA]. |
==Reference== | ==Reference== | ||
- | Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin., Liu CC, Brustad E, Liu W, Schultz PG, J Am Chem Soc. 2007 Sep 5;129(35):10648-9. Epub 2007 Aug 9. PMID:[http:// | + | Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin., Liu CC, Brustad E, Liu W, Schultz PG, J Am Chem Soc. 2007 Sep 5;129(35):10648-9. Epub 2007 Aug 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17685615 17685615] |
[[Category: Hirudo medicinalis]] | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: thrombin]] | [[Category: thrombin]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:18:12 2008'' |
Revision as of 16:18, 20 March 2008
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, resolution 1.840Å | |||||||
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Ligands: | and | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Crystal structure of sulfo-hirudin complexed to thrombin
Disease
Known diseases associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
2PW8 is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin., Liu CC, Brustad E, Liu W, Schultz PG, J Am Chem Soc. 2007 Sep 5;129(35):10648-9. Epub 2007 Aug 9. PMID:17685615
Page seeded by OCA on Thu Mar 20 18:18:12 2008
Categories: Hirudo medicinalis | Homo sapiens | Protein complex | Brustad, E. | Liu, C C. | Liu, W. | Schultz, P G. | NA | NI | Hirudin | Hydrolase | Sulfotyrosine | Thrombin