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2pzf
From Proteopedia
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| - | [[Image:2pzf.gif|left|200px]] | + | [[Image:2pzf.gif|left|200px]] |
| - | + | ||
| - | '''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508''' | + | {{Structure |
| + | |PDB= 2pzf |SIZE=350|CAPTION= <scene name='initialview01'>2pzf</scene>, resolution 2.000Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508''' | ||
| + | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2PZF is a [ | + | 2PZF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZF OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: nbd]] | [[Category: nbd]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:19:51 2008'' |
Revision as of 16:19, 20 March 2008
| |||||||
| , resolution 2.000Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | and | ||||||
| Gene: | CFTR, ABCC7 (Homo sapiens) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508
Disease
Known diseases associated with this structure: Congenital bilateral absence of vas deferens OMIM:[602421], Cystic fibrosis OMIM:[602421], Hypertrypsinemia, neonatal OMIM:[602421], Pancreatitis, idiopathic OMIM:[602421], Sweat chloride elevation without CF OMIM:[602421]
About this Structure
2PZF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:19:51 2008
Categories: Homo sapiens | Single protein | Atwell, S. | Conners, K. | Emtage, S. | Gheyi, T. | Glenn, N R. | Hendle, J. | Lewis, H A. | Lu, F. | Rodgers, L A. | Romero, R. | Sauder, J M. | Smith, D. | Tien, H. | Wasserman, S R. | Zhao, X. | ATP | MG | Abc transporter | Cftr | F508 | Hydrolase | Nbd
