2q1b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2q1b.jpg|left|200px]]<br /><applet load="2q1b" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:2q1b.jpg|left|200px]]
-
caption="2q1b, resolution 1.70&Aring;" />
+
 
-
'''Carbonic Anhydrase II in Complex with Saccharin'''<br />
+
{{Structure
 +
|PDB= 2q1b |SIZE=350|CAPTION= <scene name='initialview01'>2q1b</scene>, resolution 1.70&Aring;
 +
|SITE=
 +
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene> and <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE'>LSA</scene>
 +
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
 +
|GENE=
 +
}}
 +
 
 +
'''Carbonic Anhydrase II in Complex with Saccharin'''
 +
 
==Disease==
==Disease==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
2Q1B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HG:'>HG</scene>, <scene name='pdbligand=BEZ:'>BEZ</scene> and <scene name='pdbligand=LSA:'>LSA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1B OCA].
+
2Q1B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1B OCA].
==Reference==
==Reference==
-
Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17705204 17705204]
+
Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17705204 17705204]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 25: Line 34:
[[Category: twisted beta-sheet]]
[[Category: twisted beta-sheet]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:35:06 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:20:30 2008''

Revision as of 16:20, 20 March 2008

Image:2q1b.jpg


PDB ID 2q1b

Drag the structure with the mouse to rotate
, resolution 1.70Å
Ligands: , , and
Activity: Carbonate dehydratase, with EC number 4.2.1.1
Coordinates: save as pdb, mmCIF, xml



Carbonic Anhydrase II in Complex with Saccharin


Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

2Q1B is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:17705204

Page seeded by OCA on Thu Mar 20 18:20:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2q1b"
Personal tools