4ue8
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Complex of d. melanogaster EIF4E with the 4E binding protein thor== |
| - | + | <StructureSection load='4ue8' size='340' side='right' caption='[[4ue8]], [[Resolution|resolution]] 1.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ue8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UE8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P4G:1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE'>P4G</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ue9|4ue9]], [[4uea|4uea]], [[4ueb|4ueb]], [[4uec|4uec]], [[4ued|4ued]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ue8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ue8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ue8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ue8 PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IF4E_DROME IF4E_DROME]] Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.<ref>PMID:8663200</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Peter, D]] | [[Category: Peter, D]] | ||
[[Category: Weichenrieder, O]] | [[Category: Weichenrieder, O]] | ||
| + | [[Category: 4e binding protein]] | ||
| + | [[Category: Cap binding protein]] | ||
| + | [[Category: Gene regulation]] | ||
| + | [[Category: Translation]] | ||
| + | [[Category: Translational repression]] | ||
Revision as of 14:04, 25 February 2015
Complex of d. melanogaster EIF4E with the 4E binding protein thor
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