2q38

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[[Image:2q38.jpg|left|200px]]<br /><applet load="2q38" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2q38.jpg|left|200px]]
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caption="2q38, resolution 1.95&Aring;" />
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'''Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom'''<br />
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{{Structure
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|PDB= 2q38 |SIZE=350|CAPTION= <scene name='initialview01'>2q38</scene>, resolution 1.95&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
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|GENE=
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}}
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'''Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2Q38 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HG:'>HG</scene>, <scene name='pdbligand=LSA:'>LSA</scene>, <scene name='pdbligand=BEZ:'>BEZ</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q38 OCA].
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2Q38 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q38 OCA].
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==Reference==
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Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17705204 17705204]
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[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: ten stranded twisted beta sheet]]
[[Category: ten stranded twisted beta sheet]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:35:28 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:24:03 2008''

Revision as of 16:24, 20 March 2008

Image:2q38.jpg


PDB ID 2q38

Drag the structure with the mouse to rotate
, resolution 1.95Å
Ligands: , , , and
Activity: Carbonate dehydratase, with EC number 4.2.1.1
Coordinates: save as pdb, mmCIF, xml



Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom


Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

2Q38 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:24:03 2008

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OCA

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