4xxv
From Proteopedia
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| - | ''' | + | ==Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD== |
| - | + | <StructureSection load='4xxv' size='340' side='right' caption='[[4xxv]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xxv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XXV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XXV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iwh|4iwh]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xxv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xxv RCSB], [http://www.ebi.ac.uk/pdbsum/4xxv PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LEU3_BURTA LEU3_BURTA]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: 3-isopropylmalate dehydrogenase]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Nad]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Ssgcid]] | ||
Revision as of 14:07, 25 February 2015
Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD
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