4owz

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'''Unreleased structure'''
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==Structure of ECP/H15A mutant.==
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<StructureSection load='4owz' size='340' side='right' caption='[[4owz]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
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The entry 4owz is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4owz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OWZ FirstGlance]. <br>
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Authors: Blanco, J.A., Salazar, V.A., Boix, E., Moussaoui, M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a2y|4a2y]], [[4oxb|4oxb]], [[4oxf|4oxf]]</td></tr>
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Description: Structure of ECP/H15A mutant.
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4owz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4owz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4owz RCSB], [http://www.ebi.ac.uk/pdbsum/4owz PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Blanco, J.A]]
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== Function ==
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[[http://www.uniprot.org/uniprot/ECP_HUMAN ECP_HUMAN]] Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.<ref>PMID:2501794</ref> <ref>PMID:19450231</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Blanco, J A]]
[[Category: Boix, E]]
[[Category: Boix, E]]
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[[Category: Salazar, V.A]]
 
[[Category: Moussaoui, M]]
[[Category: Moussaoui, M]]
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[[Category: Salazar, V A]]
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[[Category: Eosinophil cationic protein]]
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[[Category: Rnase 3]]

Revision as of 11:33, 4 March 2015

Structure of ECP/H15A mutant.

4owz, resolution 1.47Å

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