Casein kinase
From Proteopedia
(Difference between revisions)
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**[[3uys]] – hCK1-δ<br /> | **[[3uys]] – hCK1-δ<br /> | ||
**[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]] – hCK1-δ + inhibitor<br /> | **[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]] – hCK1-δ + inhibitor<br /> | ||
| + | **[[4tw9]], [[4twc]] – hCK1-δ (mutant) + inhibitor<br /> | ||
**[[1cki]] – rCK1-δ (mutant) – rat<br /> | **[[1cki]] – rCK1-δ (mutant) – rat<br /> | ||
**[[1ckj]] - rCK1-δ (mutant) + WO4<br /> | **[[1ckj]] - rCK1-δ (mutant) + WO4<br /> | ||
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**[[1na7]], [[3fwq]], [[3juh]] - hCK2 α subunit (mutant)<br /> | **[[1na7]], [[3fwq]], [[3juh]] - hCK2 α subunit (mutant)<br /> | ||
**[[3axw]], [[3r0t]], [[3u4u]] – hCK2 α subunit + inhibitor<br /> | **[[3axw]], [[3r0t]], [[3u4u]] – hCK2 α subunit + inhibitor<br /> | ||
| - | **[[3u87]] – hCK2 α subunit + ATP analog<br /> | ||
| - | **[[3q9w]], [[3q9x]] – hCK2 α subunit + emodin<br /> | ||
| - | **[[3q9y]], [[3q9z]] – hCK2 α subunit + quinalizarin<br /> | ||
| - | **[[3u9c]] – hCK2 α subunit + resorufin<br /> | ||
**[[3ofm]] - hCK2 α’ subunit <br /> | **[[3ofm]] - hCK2 α’ subunit <br /> | ||
**[[2r7i]] - rCK2 α subunit <br /> | **[[2r7i]] - rCK2 α subunit <br /> | ||
**[[1lpu]], [[1lr4]], [[1jam]] - mCK2 α subunit <br /> | **[[1lpu]], [[1lr4]], [[1jam]] - mCK2 α subunit <br /> | ||
| - | **[[1daw]], [[1day]] – mCK2 + Mg-AMPPNP <br /> | ||
| - | **[[1f0q]], [[3pzh]] – mCK2 α subunit + emodin<br /> | ||
| - | **[[1zoe]], [[1zog]], [[1zoh]] – mCK2 α subunit + TBB derivative<br /> | ||
*CK2 catalytic subunit binary complex | *CK2 catalytic subunit binary complex | ||
| + | **[[3u87]] – hCK2 α subunit + ATP analog<br /> | ||
| + | **[[3q9w]], [[3q9x]] – hCK2 α subunit + emodin<br /> | ||
| + | **[[3q9y]], [[3q9z]] – hCK2 α subunit + quinalizarin<br /> | ||
| + | **[[3u9c]] – hCK2 α subunit + resorufin<br /> | ||
**[[2pvr]] - hCK2 α subunit + sulfate<br /> | **[[2pvr]] - hCK2 α subunit + sulfate<br /> | ||
**[[3rp0]] – hCK2 α subunit + α’ subunit + ATP analog | **[[3rp0]] – hCK2 α subunit + α’ subunit + ATP analog | ||
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**[[3bqc]], [[3c13]] - hCK2 α subunit + emodin | **[[3bqc]], [[3c13]] - hCK2 α subunit + emodin | ||
| - | **[[1j91]] - mCK2 α subunit + ATP competitive inhibitor - maize | + | **[[1j91]], [[4rlk]] - mCK2 α subunit + ATP competitive inhibitor - maize |
| - | **[[1lp4]] - mCK2 α subunit + Mg-AMPPNP | + | **[[1lp4]], [[1daw]], [[1day]] - mCK2 α subunit + Mg-AMPPNP |
| - | **[[3nsz]] - hCK2 α subunit + AMPPN<br /> | + | **[[3nsz]], [[3wow]] - hCK2 α subunit + AMPPN<br /> |
**[[3w8l]] - hCK2 α subunit (mutant) + inositol hexakisphosphate<br /> | **[[3w8l]] - hCK2 α subunit (mutant) + inositol hexakisphosphate<br /> | ||
**[[4dgm]] - mCK2 α subunit + apigenin<br /> | **[[4dgm]] - mCK2 α subunit + apigenin<br /> | ||
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**[[1m2p]], [[1m2q]], [[1m2r]], [[1om1]], [[2oxd]], [[2oxx]], [[2oxy]], [[2qc6]], [[2pvh]], [[3fl5]], [[3kxg]], [[3kxh]], [[3kxm]], [[3kxn]], [[3pvg]], [[3pwd]] - mCK2 α subunit + inhibitor | **[[1m2p]], [[1m2q]], [[1m2r]], [[1om1]], [[2oxd]], [[2oxx]], [[2oxy]], [[2qc6]], [[2pvh]], [[3fl5]], [[3kxg]], [[3kxh]], [[3kxm]], [[3kxn]], [[3pvg]], [[3pwd]] - mCK2 α subunit + inhibitor | ||
| - | **[[3e3b]], [[2zjw]], [[3h30]], [[3mb6]], [[3mb7]], [[3nga]], [[3rps]], [[3pe1]], [[3pe2]], [[3amy]], [[3at3]], [[3at4]], [[4anm]], [[4grb]], [[4gub]] - hCK2 α subunit + inhibitor<br /> | + | **[[3e3b]], [[2zjw]], [[3h30]], [[3mb6]], [[3mb7]], [[3nga]], [[3rps]], [[3pe1]], [[3pe2]], [[3amy]], [[3at3]], [[3at4]], [[4anm]], [[4grb]], [[4gub]], [[3axw]], [[3r0t]], [[3u4u]], [[3owj]], [[3owk]], [[3owl]], [[3wik]], [[3wil]], [[4bxa]], [[4bxb]], [[4kwp]], [[4rll]] - hCK2 α subunit + inhibitor<br /> |
**[[4fbx]] - hCK2 α subunit + polypeptide inhibitor<br /> | **[[4fbx]] - hCK2 α subunit + polypeptide inhibitor<br /> | ||
**[[4ib5]] - hCK2 α subunit + hCK2 β polypeptide <br /> | **[[4ib5]] - hCK2 α subunit + hCK2 β polypeptide <br /> | ||
**[[2pvh]], [[2pvj]], [[2pvk]], [[2pvl]], [[2pvm]], [[2pvn]], [[3be9]] - mCK2 α subunit (mutant) + inhibitor<br /> | **[[2pvh]], [[2pvj]], [[2pvk]], [[2pvl]], [[2pvm]], [[2pvn]], [[3be9]] - mCK2 α subunit (mutant) + inhibitor<br /> | ||
| + | **[[1f0q]], [[3pzh]] – mCK2 α subunit + emodin<br /> | ||
| + | **[[1zoe]], [[1zog]], [[1zoh]] – mCK2 α subunit + TBB derivative<br /> | ||
**[[4fi1]], [[4mwh]] - yCK2 α subunit + ATP<br /> | **[[4fi1]], [[4mwh]] - yCK2 α subunit + ATP<br /> | ||
| + | **[[4jqe]] - yCK2 α subunit + AMPPN<br /> | ||
| + | **[[4jr7]], [[4lfi]] - yCK2 α subunit + GMPPNP<br /> | ||
*CK2 regulatory subunit | *CK2 regulatory subunit | ||
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**[[1jwh]], [[4md7]] - hCK2 α subunit + β subunit<br /> | **[[1jwh]], [[4md7]] - hCK2 α subunit + β subunit<br /> | ||
**[[4dgl]], [[4md8]], [[4md9]] - hCK2 α subunit (mutant) + β subunit<br /> | **[[4dgl]], [[4md8]], [[4md9]] - hCK2 α subunit (mutant) + β subunit<br /> | ||
| + | **[[4nh1]] - hCK2 α subunit + β subunit (mutant)<br /> | ||
**[[1ds5]] - mCK2 α subunit + β subunit peptide | **[[1ds5]] - mCK2 α subunit + β subunit peptide | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:49, 10 March 2015
Casein kinase (CK) is a protein kinase which functions as regulators of signal transduction. CK1 is a serine/threonine kinase with several members: α, β1, γ1, γ2, γ3, δ and ε. CK2 functions in cell cycle control, DNA repair and circadian rhythm regulation. CK2 is a tetramer with a pair of 2 subunits – the α subunit is the catalytic one and the β subunit is the regulatory one.
3D Structures of casein kinase
Updated on 10-March-2015
