3j9c
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution== |
| - | + | <StructureSection load='3j9c' size='340' side='right' caption='[[3j9c]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3j9c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J9C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J9C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j9c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j9c RCSB], [http://www.ebi.ac.uk/pdbsum/3j9c PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN]] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Collier, R J]] | ||
[[Category: Jiang, J]] | [[Category: Jiang, J]] | ||
| - | [[Category: | + | [[Category: Pentelute, B L]] |
| + | [[Category: Zhou, Z H]] | ||
| + | [[Category: Anthrax toxin]] | ||
| + | [[Category: Bacterial toxin]] | ||
| + | [[Category: Protective antigen]] | ||
| + | [[Category: Protein translocation channel]] | ||
| + | [[Category: Toxin]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 11:52, 11 March 2015
CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution
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