4p3o
From Proteopedia
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| - | ''' | + | ==Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 2== |
| - | + | <StructureSection load='4p3o' size='340' side='right' caption='[[4p3o]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4p3o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P3O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2CR:(1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADECA-4,6-DIEN-2-YL]CYCLOPENTANECARBOXYLIC+ACID'>2CR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p3n|4p3n]], [[4p3p|4p3p]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine--tRNA_ligase Threonine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.3 6.1.1.3] </span></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p3o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p3o RCSB], [http://www.ebi.ac.uk/pdbsum/4p3o PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/SYT_ECOLI SYT_ECOLI]] ThrS is also a translational repressor protein, it controls the translation of its own gene by binding to its mRNA.[HAMAP-Rule:MF_00184] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Threonine--tRNA ligase]] | ||
| + | [[Category: Chen, K]] | ||
[[Category: Chen, X]] | [[Category: Chen, X]] | ||
[[Category: Fang, P]] | [[Category: Fang, P]] | ||
| - | [[Category: | + | [[Category: Guo, M]] |
| + | [[Category: Yu, X]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Synthetase]] | ||
Revision as of 11:53, 11 March 2015
Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 2
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Categories: Threonine--tRNA ligase | Chen, K | Chen, X | Fang, P | Guo, M | Yu, X | Inhibitor | Synthetase
