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4u3x
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Structure of a human VH antibody domain binding to the cleft of hen egg lysozyme== |
| - | + | <StructureSection load='4u3x' size='340' side='right' caption='[[4u3x]], [[Resolution|resolution]] 2.26Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4u3x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pgj|4pgj]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u3x RCSB], [http://www.ebi.ac.uk/pdbsum/4u3x PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Lysozyme]] | ||
[[Category: Christ, D]] | [[Category: Christ, D]] | ||
| + | [[Category: Langley, D B]] | ||
[[Category: Rouet, R]] | [[Category: Rouet, R]] | ||
| + | [[Category: Antibody-antigen complex structure]] | ||
| + | [[Category: Human vh domain antibody]] | ||
| + | [[Category: Hydrolase-immune system complex]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Phage display]] | ||
Revision as of 11:58, 11 March 2015
Structure of a human VH antibody domain binding to the cleft of hen egg lysozyme
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