This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4x94
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (hexagonal form)== |
| - | + | <StructureSection load='4x94' size='340' side='right' caption='[[4x94]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x94]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X94 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X94 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x90|4x90]], [[4x91|4x91]], [[4x92|4x92]], [[4x93|4x93]], [[4x95|4x95]], [[4x96|4x96]], [[4x97|4x97]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x94 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x94 RCSB], [http://www.ebi.ac.uk/pdbsum/4x94 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PAG15_HUMAN PAG15_HUMAN]] Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phospholipid (By similarity). May have weak lysophospholipase activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Glukhova, A]] | [[Category: Glukhova, A]] | ||
| - | [[Category: Tesmer, J | + | [[Category: Tesmer, J J.G]] |
| + | [[Category: Acyltransferase]] | ||
| + | [[Category: Esterase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Phospholipase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 12:00, 11 March 2015
Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (hexagonal form)
| |||||||||||
