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2qzr

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[[Image:2qzr.jpg|left|200px]]<br /><applet load="2qzr" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2qzr.jpg|left|200px]]
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caption="2qzr, resolution 1.95&Aring;" />
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'''tRNA-Guanine Transglycosylase(TGT) in Complex with 6-amino-2-[(1-naphthylmethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one'''<br />
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{{Structure
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|PDB= 2qzr |SIZE=350|CAPTION= <scene name='initialview01'>2qzr</scene>, resolution 1.95&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=S79:6-amino-2-[(1-naphthylmethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one'>S79</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29]
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|GENE= tgt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=542 Zymomonas mobilis])
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}}
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'''tRNA-Guanine Transglycosylase(TGT) in Complex with 6-amino-2-[(1-naphthylmethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one'''
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==About this Structure==
==About this Structure==
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2QZR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=S79:'>S79</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZR OCA].
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2QZR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZR OCA].
==Reference==
==Reference==
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Potent inhibitors of tRNA-guanine transglycosylase, an enzyme linked to the pathogenicity of the Shigella bacterium: charge-assisted hydrogen bonding., Hortner SR, Ritschel T, Stengl B, Kramer C, Schweizer WB, Wagner B, Kansy M, Klebe G, Diederich F, Angew Chem Int Ed Engl. 2007;46(43):8266-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17902085 17902085]
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Potent inhibitors of tRNA-guanine transglycosylase, an enzyme linked to the pathogenicity of the Shigella bacterium: charge-assisted hydrogen bonding., Hortner SR, Ritschel T, Stengl B, Kramer C, Schweizer WB, Wagner B, Kansy M, Klebe G, Diederich F, Angew Chem Int Ed Engl. 2007;46(43):8266-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17902085 17902085]
[[Category: Queuine tRNA-ribosyltransferase]]
[[Category: Queuine tRNA-ribosyltransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: zinc]]
[[Category: zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:43:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:31:14 2008''

Revision as of 16:31, 20 March 2008

Image:2qzr.jpg


PDB ID 2qzr

Drag the structure with the mouse to rotate
, resolution 1.95Å
Ligands: , and
Gene: tgt (Zymomonas mobilis)
Activity: Queuine tRNA-ribosyltransferase, with EC number 2.4.2.29
Coordinates: save as pdb, mmCIF, xml



tRNA-Guanine Transglycosylase(TGT) in Complex with 6-amino-2-[(1-naphthylmethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one


About this Structure

2QZR is a Single protein structure of sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

Potent inhibitors of tRNA-guanine transglycosylase, an enzyme linked to the pathogenicity of the Shigella bacterium: charge-assisted hydrogen bonding., Hortner SR, Ritschel T, Stengl B, Kramer C, Schweizer WB, Wagner B, Kansy M, Klebe G, Diederich F, Angew Chem Int Ed Engl. 2007;46(43):8266-9. PMID:17902085

Page seeded by OCA on Thu Mar 20 18:31:14 2008

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