4pv5
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of mouse glyoxalase I in complexed with 18-beta-glycyrrhetinic acid== |
| - | + | <StructureSection load='4pv5' size='340' side='right' caption='[[4pv5]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4pv5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PV5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PV5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBW:(3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC+ACID'>CBW</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lactoylglutathione_lyase Lactoylglutathione lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.5 4.4.1.5] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pv5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pv5 RCSB], [http://www.ebi.ac.uk/pdbsum/4pv5 PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/LGUL_MOUSE LGUL_MOUSE]] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lactoylglutathione lyase]] | ||
| + | [[Category: Hu, X]] | ||
[[Category: Li, C]] | [[Category: Li, C]] | ||
| + | [[Category: Zhai, J]] | ||
| + | [[Category: Zhang, H]] | ||
[[Category: Zhang, L]] | [[Category: Zhang, L]] | ||
[[Category: Zhao, Y]] | [[Category: Zhao, Y]] | ||
| - | [[Category: | + | [[Category: Lyase-lyase inhibitor complex]] |
| - | + | ||
Revision as of 12:12, 18 March 2015
Crystal structure of mouse glyoxalase I in complexed with 18-beta-glycyrrhetinic acid
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