This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4rzf
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ''' | + | ==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant== |
| - | + | <StructureSection load='4rzf' size='340' side='right' caption='[[4rzf]], [[Resolution|resolution]] 1.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rzf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rze|4rze]], [[4rzg|4rzg]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rzf RCSB], [http://www.ebi.ac.uk/pdbsum/4rzf PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref> |
| - | [[ | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Chen, H]] | ||
| + | [[Category: Li, A]] | ||
| + | [[Category: Li, F]] | ||
[[Category: Li, L]] | [[Category: Li, L]] | ||
| - | [[Category: | + | [[Category: Lin, T]] |
| + | [[Category: Liu, Y]] | ||
| + | [[Category: Tian, X]] | ||
| + | [[Category: Wu, Q]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 12:14, 18 March 2015
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, S441W mutant
| |||||||||||
Categories: Chen, H | Li, A | Li, F | Li, L | Lin, T | Liu, Y | Tian, X | Wu, Q | Transcription
