4rzg
From Proteopedia
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| - | ''' | + | ==Crystal Structure Analysis of the DNPA-bounded NUR77 Ligand binding Domain== |
| - | + | <StructureSection load='4rzg' size='340' side='right' caption='[[4rzg]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4rzg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZHN:PENTYL+(3,5-DIHYDROXY-2-NONANOYLPHENYL)ACETATE'>ZHN</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rze|4rze]], [[4rzf|4rzf]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rzg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rzg RCSB], [http://www.ebi.ac.uk/pdbsum/4rzg PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref> |
| - | [[ | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Chen, H]] | ||
| + | [[Category: Li, A]] | ||
| + | [[Category: Li, F]] | ||
[[Category: Li, L]] | [[Category: Li, L]] | ||
| - | [[Category: | + | [[Category: Lin, T]] |
| + | [[Category: Liu, Y]] | ||
| + | [[Category: Tian, X]] | ||
| + | [[Category: Wu, Q]] | ||
| + | [[Category: Nur77-lbd and dnpa complex]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 12:14, 18 March 2015
Crystal Structure Analysis of the DNPA-bounded NUR77 Ligand binding Domain
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Categories: Chen, H | Li, A | Li, F | Li, L | Lin, T | Liu, Y | Tian, X | Wu, Q | Nur77-lbd and dnpa complex | Transcription
