2r6a

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[[Image:2r6a.jpg|left|200px]]<br /><applet load="2r6a" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2r6a.jpg|left|200px]]
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caption="2r6a, resolution 2.90&Aring;" />
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'''Crystal Form BH1'''<br />
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{{Structure
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|PDB= 2r6a |SIZE=350|CAPTION= <scene name='initialview01'>2r6a</scene>, resolution 2.90&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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|ACTIVITY=
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|GENE= DnaB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus]), DnaG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])
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}}
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'''Crystal Form BH1'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2R6A is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R6A OCA].
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2R6A is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R6A OCA].
==Reference==
==Reference==
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Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase., Bailey S, Eliason WK, Steitz TA, Science. 2007 Oct 19;318(5849):459-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17947583 17947583]
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Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase., Bailey S, Eliason WK, Steitz TA, Science. 2007 Oct 19;318(5849):459-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17947583 17947583]
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: replication]]
[[Category: replication]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:44:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:32:57 2008''

Revision as of 16:32, 20 March 2008

Image:2r6a.jpg


PDB ID 2r6a

Drag the structure with the mouse to rotate
, resolution 2.90Å
Ligands:
Gene: DnaB (Geobacillus stearothermophilus), DnaG (Geobacillus stearothermophilus)
Coordinates: save as pdb, mmCIF, xml



Crystal Form BH1


Overview

The complex between the DnaB helicase and the DnaG primase unwinds duplex DNA at the eubacterial replication fork and synthesizes the Okazaki RNA primers. The crystal structures of hexameric DnaB and its complex with the helicase binding domain (HBD) of DnaG reveal that within the hexamer the two domains of DnaB pack with strikingly different symmetries to form a distinct two-layered ring structure. Each of three bound HBDs stabilizes the DnaB hexamer in a conformation that may increase its processivity. Three positive, conserved electrostatic patches on the N-terminal domain of DnaB may also serve as a binding site for DNA and thereby guide the DNA to a DnaG active site.

About this Structure

2R6A is a Protein complex structure of sequences from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase., Bailey S, Eliason WK, Steitz TA, Science. 2007 Oct 19;318(5849):459-63. PMID:17947583

Page seeded by OCA on Thu Mar 20 18:32:57 2008

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