2rfi

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[[Image:2rfi.jpg|left|200px]]<br /><applet load="2rfi" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2rfi.jpg|left|200px]]
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caption="2rfi, resolution 1.59&Aring;" />
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'''Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide'''<br />
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{{Structure
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|PDB= 2rfi |SIZE=350|CAPTION= <scene name='initialview01'>2rfi</scene>, resolution 1.59&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43]
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|GENE= EHMT1, EUHMTASE1, KIAA1876 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2RFI is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFI OCA].
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2RFI is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFI OCA].
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: s-adenosyl-l-methionine]]
[[Category: s-adenosyl-l-methionine]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:46:51 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:35 2008''

Revision as of 16:35, 20 March 2008

Image:2rfi.jpg


PDB ID 2rfi

Drag the structure with the mouse to rotate
, resolution 1.59Å
Ligands: and
Gene: EHMT1, EUHMTASE1, KIAA1876 (Homo sapiens)
Activity: Histone-lysine N-methyltransferase, with EC number 2.1.1.43
Coordinates: save as pdb, mmCIF, xml



Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide


Disease

Known diseases associated with this structure: Chromosome 9q subtelomeric deletion syndrome OMIM:[607001]

About this Structure

2RFI is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:35:35 2008

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OCA

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