4w52
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==T4 Lysozyme L99A with Benzene Bound== |
| - | + | <StructureSection load='4w52' size='340' side='right' caption='[[4w52]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4w52]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W52 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W52 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BNZ:BENZENE'>BNZ</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w52 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w52 RCSB], [http://www.ebi.ac.uk/pdbsum/4w52 PDBsum]</span></td></tr> | |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lysozyme]] | ||
[[Category: Eidam, O]] | [[Category: Eidam, O]] | ||
| + | [[Category: Fischer, M]] | ||
| + | [[Category: Merski, M]] | ||
| + | [[Category: Shoichet, B K]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 13:20, 1 April 2015
T4 Lysozyme L99A with Benzene Bound
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Categories: Lysozyme | Eidam, O | Fischer, M | Merski, M | Shoichet, B K | Hydrolase
