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4xli

From Proteopedia

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m (Protected "4xli" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Crystal structure of Abl2/Arg kinase in complex with dasatinib==
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<StructureSection load='4xli' size='340' side='right' caption='[[4xli]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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The entry 4xli is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4xli]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XLI FirstGlance]. <br>
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Authors: Ha, B.H., Boggon, T.J.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1N1:N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE'>1N1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
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Description:
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xli RCSB], [http://www.ebi.ac.uk/pdbsum/4xli PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Ha, B.H]]
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__TOC__
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[[Category: Boggon, T.J]]
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</StructureSection>
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Boggon, T J]]
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[[Category: Ha, B H]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 13:21, 1 April 2015

Crystal structure of Abl2/Arg kinase in complex with dasatinib

4xli, resolution 2.50Å

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