4xli
From Proteopedia
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- | ''' | + | ==Crystal structure of Abl2/Arg kinase in complex with dasatinib== |
- | + | <StructureSection load='4xli' size='340' side='right' caption='[[4xli]], [[Resolution|resolution]] 2.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4xli]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XLI FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1N1:N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE'>1N1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
- | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xli RCSB], [http://www.ebi.ac.uk/pdbsum/4xli PDBsum]</span></td></tr> | |
- | [[Category: | + | </table> |
- | [[Category: Ha, B | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
+ | [[Category: Non-specific protein-tyrosine kinase]] | ||
+ | [[Category: Boggon, T J]] | ||
+ | [[Category: Ha, B H]] | ||
+ | [[Category: Inhibitor]] | ||
+ | [[Category: Kinase]] | ||
+ | [[Category: Transferase]] | ||
+ | [[Category: Transferase-transferase inhibitor complex]] |
Revision as of 13:21, 1 April 2015
Crystal structure of Abl2/Arg kinase in complex with dasatinib
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