Fibroblast growth factor
From Proteopedia
(Difference between revisions)
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**[[3hal]] – FGF1 - rabbit <br /> | **[[3hal]] – FGF1 - rabbit <br /> | ||
**[[2afg]], [[1jqz]], [[1rg8]] – hFGF1 - human <br /> | **[[2afg]], [[1jqz]], [[1rg8]] – hFGF1 - human <br /> | ||
| - | **[[1jt3]], [[1jt4]], [[1jt5]], [[1jt7]], [[1jtc]], [[1k5u]], [[1k5v]], [[1m16]], [[1jy0]], [[1nzk]], [[1p63]], [[1pzz]], [[1q03]], [[1q04]], [[1yto]], [[1z2v]], [[1z4s]], [[2aqz]], [[2hw9]], [[2hwa]], [[2hwm]], [[2hz9]], [[2ntd]], [[3b9u]], [[3ba4]], [[3ba5]], [[3ba7]], [[3bad]], [[3bag]], [[3bah]], [[3bao]], [[3baq]], [[3bau]], [[3bav]], [[3bb2]], [[2q9x]], [[3crg]], [[3crh]], [[3cri]], [[3cqa]], [[3fgm]], [[3fj8]], [[3fj9]], [[3fja]], [[3fjb]], [[3fjc]], [[3fjd]], [[3fje]], [[3fjf]], [[3fjh]], [[3fji]], [[3fjj]], [[3fjk]], [[3hom]], [[3o3q]] – hFGF1 (mutant) <br /> | + | **[[1jt3]], [[1jt4]], [[1jt5]], [[1jt7]], [[1jtc]], [[1k5u]], [[1k5v]], [[1m16]], [[1jy0]], [[1nzk]], [[1p63]], [[1pzz]], [[1q03]], [[1q04]], [[1yto]], [[1z2v]], [[1z4s]], [[2aqz]], [[2hw9]], [[2hwa]], [[2hwm]], [[2hz9]], [[2ntd]], [[3b9u]], [[3ba4]], [[3ba5]], [[3ba7]], [[3bad]], [[3bag]], [[3bah]], [[3bao]], [[3baq]], [[3bau]], [[3bav]], [[3bb2]], [[2q9x]], [[3crg]], [[3crh]], [[3cri]], [[3cqa]], [[3fgm]], [[3fj8]], [[3fj9]], [[3fja]], [[3fjb]], [[3fjc]], [[3fjd]], [[3fje]], [[3fjf]], [[3fjh]], [[3fji]], [[3fjj]], [[3fjk]], [[3hom]], [[3o3q]], [[4q91]], [[4q9g]], [[4q9p]], [[4qal]], [[4qbc]], [[4qbv]], [[4qc4]] – hFGF1 (mutant) <br /> |
**[[1dzd]], [[2rq9]] – hFGF1 - NMR <br /> | **[[1dzd]], [[2rq9]] – hFGF1 - NMR <br /> | ||
**[[1dzc]] – hFGF1 (mutant) - NMR <br /> | **[[1dzc]] – hFGF1 (mutant) - NMR <br /> | ||
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**[[1ry7]] – hFGF1 + hFGFR3<br /> | **[[1ry7]] – hFGF1 + hFGFR3<br /> | ||
**[[3cu1]] – hFGF1 + hFGFR2<br /> | **[[3cu1]] – hFGF1 + hFGFR2<br /> | ||
| + | **[[4j23]] – hFGF1 + hFGFR2 + inhibitor<br /> | ||
*FGF2 | *FGF2 | ||
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**[[1ev2]] - hFGF2 (mutant) + hFGFR2 <br /> | **[[1ev2]] - hFGF2 (mutant) + hFGFR2 <br /> | ||
**[[2m49]] - hFGF2 (mutant) + S100-B <br /> | **[[2m49]] - hFGF2 (mutant) + S100-B <br /> | ||
| + | **[[4oee]], [[4oef]], [[4oeg]] - hFGF2 (mutant) + disaccharide <br /> | ||
*FGF4 | *FGF4 | ||
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**[[3hbw]] – hFGF13 <br /> | **[[3hbw]] – hFGF13 <br /> | ||
**[[4dck]] – hFGF13 + calmodulin + sodium channel subunit α <br /> | **[[4dck]] – hFGF13 + calmodulin + sodium channel subunit α <br /> | ||
| + | |||
| + | *FGF18 | ||
| + | |||
| + | **[[4cjm]] – hFGF18 <br /> | ||
*FGF19 | *FGF19 | ||
Revision as of 11:12, 2 April 2015
Fibroblast growth factors (FGF) are involved in angiogenesis, wound-healing and embryonic development. FGF is heparin-binding protein. FGF require heparan sulfate (HS) to activate the four FGF cell-surface receptors (FGFR). In vertebrates there are 23 members in the FGF family. FGF signaling is important in the pathogenesis of a variety of tumor types.
- FGF1 is called acidic FGF.
- FGF2 is called basic FGF.
- FGF7 is called keratinocyte growth factor which is present in the eiptheliazation-phase of wound healing when keratinocytes are covering the wound.
3D structures of fibroblast growth factor
Updated on 02-April-2015
