Glutaminase
From Proteopedia
(Difference between revisions)
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**[[2zk9]] – CpGLN – ''Chryseobacterium proteolyticum''<br /> | **[[2zk9]] – CpGLN – ''Chryseobacterium proteolyticum''<br /> | ||
**[[3a54]], [[3a55]], [[3a56]] – CpGLN (mutant)<br /> | **[[3a54]], [[3a55]], [[3a56]] – CpGLN (mutant)<br /> | ||
| + | **[[2ksv]] – CpGLN - NMR<br /> | ||
**[[3agf]] - BsGLN – ''Bacillus subtilis''<br /> | **[[3agf]] - BsGLN – ''Bacillus subtilis''<br /> | ||
**[[3ss3]], [[3ss4]] – mGLN C – mouse<br /> | **[[3ss3]], [[3ss4]] – mGLN C – mouse<br /> | ||
| Line 25: | Line 26: | ||
**[[3czd]], [[3unw]] – hGLN + Glu<br /> | **[[3czd]], [[3unw]] – hGLN + Glu<br /> | ||
**[[3vp0]] – hGLN + Gln<br /> | **[[3vp0]] – hGLN + Gln<br /> | ||
| - | **[[3uo9]], [[3voz]], [[3vp2]], [[3vp3]], [[3vp4]] - hGLN + inhibitor<br /> | + | **[[3uo9]], [[3voz]], [[3vp2]], [[3vp3]], [[3vp4]], [[4o7d]] - hGLN + inhibitor<br /> |
**[[3iha]], [[3ihb]], [[3age]] - MlGLN + Glu<br /> | **[[3iha]], [[3ihb]], [[3age]] - MlGLN + Glu<br /> | ||
**[[3ss5]] – mGLN + Glu<br /> | **[[3ss5]] – mGLN + Glu<br /> | ||
Revision as of 09:02, 8 April 2015
Glutaminase (GLN) catalyzes the conversion of glutamine (Gln) to glutamic acid (Glu). GLN is present at the axonal termini of neurons where GA functions as a neurotransmitter. ADP is an activator of GLN. GLN is a homodimer. In human GLN is found as 2 isozymes – GLN and GLN 2. Glutaminase-asparaginase (GLN-ASN) can amidohydrolase both glutamine and asparagine to their corresponding Glu and Asp.
3D structures of glutaminase
Updated on 08-April-2015
Created with the participation of Lindsey Butler.
