4mxe

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'''Unreleased structure'''
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==Human establishment factor-like protein 1==
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<StructureSection load='4mxe' size='340' side='right' caption='[[4mxe]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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The entry 4mxe is ON HOLD until Apr 08 2016
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4mxe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MXE FirstGlance]. <br>
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Authors: Karlberg, T., Wisniewska, M., Thorsell, A.G., Kouznetsova, E., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Svensson, L., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mxe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mxe RCSB], [http://www.ebi.ac.uk/pdbsum/4mxe PDBsum]</span></td></tr>
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Description: Human establishment factor-like protein 1
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</table>
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[[Category: Unreleased Structures]]
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== Function ==
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[[Category: Nordlund, P]]
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[[http://www.uniprot.org/uniprot/ESCO1_HUMAN ESCO1_HUMAN]] Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.<ref>PMID:14576321</ref> <ref>PMID:15958495</ref> <ref>PMID:18614053</ref> <ref>PMID:19907496</ref>
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[[Category: Johansson, I]]
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== References ==
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[[Category: Hammarstrom, M]]
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<references/>
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[[Category: Collins, R]]
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__TOC__
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[[Category: Kouznetsova, E]]
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</StructureSection>
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[[Category: Graslund, S]]
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[[Category: Arrowsmith, C H]]
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[[Category: Wisniewska, M]]
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[[Category: Berg, S Van Den]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Wahlberg, E]]
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[[Category: Persson, C]]
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[[Category: Berglund, H]]
[[Category: Berglund, H]]
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[[Category: Flores, A]]
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[[Category: Bountra, C]]
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[[Category: Van Den Berg, S]]
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[[Category: Collins, R]]
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[[Category: Nyman, T]]
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[[Category: Edwards, A M]]
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[[Category: Kraulis, P]]
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[[Category: Thorsell, A.G]]
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[[Category: Schuler, H]]
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[[Category: Flodin, S]]
[[Category: Flodin, S]]
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[[Category: Tresaugues, L]]
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[[Category: Flores, A]]
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[[Category: Welin, M]]
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[[Category: Graslund, S]]
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[[Category: Edwards, A.M]]
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[[Category: Hammarstrom, M]]
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[[Category: Johansson, I]]
[[Category: Kallas, A]]
[[Category: Kallas, A]]
[[Category: Karlberg, T]]
[[Category: Karlberg, T]]
[[Category: Kotenyova, T]]
[[Category: Kotenyova, T]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Kouznetsova, E]]
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[[Category: Kraulis, P]]
[[Category: Moche, M]]
[[Category: Moche, M]]
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[[Category: Weigelt, J]]
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[[Category: Nielsen, T K]]
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[[Category: Svensson, L]]
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[[Category: Nordlund, P]]
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[[Category: Nielsen, T.K]]
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[[Category: Nyman, T]]
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[[Category: Bountra, C]]
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[[Category: Persson, C]]
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[[Category: Structural genomic]]
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[[Category: Schuler, H]]
[[Category: Schutz, P]]
[[Category: Schutz, P]]
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[[Category: Svensson, L]]
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[[Category: Thorsell, A G]]
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[[Category: Tresaugues, L]]
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[[Category: Wahlberg, E]]
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[[Category: Weigelt, J]]
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[[Category: Welin, M]]
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[[Category: Wisniewska, M]]
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[[Category: Acetyltransferase]]
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[[Category: Gcn5-related n-acetyltransferase fold]]
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[[Category: Nucleus]]
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[[Category: Sgc]]
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[[Category: Transferase]]

Revision as of 11:12, 8 April 2015

Human establishment factor-like protein 1

4mxe, resolution 2.60Å

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